Author

Libia A. Garcia

Cold Spring Harbor LaboratoryORCID 0000-0002-0654-0644Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Scott K. LyonsiD· 2 shared Brian A. Benz· 1 shared Charlie ChungiD· 1 shared David E. Rivadeneira· 1 shared David L. SpectoriD· 1 shared Elif Ozcelik· 1 shared Gagan Dev· 1 shared J Zhang· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Scott K. LyonsORCID

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2 papers

Recent·Most cited

Microbial induction of MHC-II expression in colon cancer cells overcomes immunotherapy resistance and limits metastasis

Charlie Chung, Elif Ozcelik, J Zhang, Zeli Shen, Onur Eskiocak, Yihan Qin, Jill Habel, Kadir Ozler, Santhilal Subhash, Zakaria Aminzada, Gagan Dev, Libia A. Garcia, Scott K. Lyons, Timothy Wesley Hand, David E. Rivadeneira, , Semir Beyaz

This study shows that a microbiome-dependent mechanism increases MHC-II expression in colon cancer cells, enhancing immunotherapy response and limiting metastasis.

bioRxiv · Jul 4, 2026 · PreprintImmunology

Platr4 is an ESC-specific lncRNA that exhibits its function downstream on meso/endoderm lineage commitment

Rasmani Hazra, Lily Brine, Libia A. Garcia, Brian A. Benz, Napon Chirathivat, Michael M. Shen, John Erby Wilkinson, Scott K. Lyons, David L. Spector

This study identifies Platr4 as an ESC-specific lncRNA that regulates meso/endoderm lineage commitment by interacting with Tead4 to control Ctgf expression, leading to cardiac defects in knockout mice.

bioRxiv · Dec 20, 2021 · PreprintDevelopmental Biology