Author

Xiaoyun Wang

University of TorontoORCID 0000-0002-0672-2480Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiaoyun Wang2 papers · Center for Excellence in Molecular Cell Science

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A.M. EdwardsiD· 1 shared Albina Bolotokova· 1 shared C.H. ArrowsmithiD· 1 shared Conrad Veranso SimobeniD· 1 shared Derek J. WilsoniD· 1 shared Esther WolfiD· 1 shared Hui PengiD· 1 shared Jianxian SuniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A.M. EdwardsORCID

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1 paper

Recent·Most cited

Identification and Characterization of a Small Molecule Ligand for the Huntingtin-HAP40 Complex

Rocher Leung, Esther Wolf, Justin C. Deme, Swati Balakrishnan, Conrad Veranso Simoben, Shulu Feng, Jonathan D. Macdonald, Renu Chandrasekaran, Jianxian Sun, Xiaoyun Wang, Albina Bolotokova, Yefen Zou, Ram Kannan, Suzanne Z. Ackloo, Derek J. Wilson, , Rachel Harding

The paper identifies a small molecule ligand for the HTT-HAP40 complex using AS-MS and validates its binding through multiple techniques, highlighting a druggable interface for HD therapeutics.

bioRxiv · Nov 21, 2025 · PreprintPharmacology & Toxicology