Author
Memorial Sloan Kettering Cancer CenterORCID 0000-0002-0674-1411Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Minsi Zhang, Ziqi Jiao, Ylenia Cendon Florez…·Gaspare La Rocca
The paper shows that inhibiting the HMWR complex causes mitotic defects and enhances cancer cell vulnerability when combined with genotoxic agents.
Vera Tiedje, Pablo Sánchez Vela, Julie L. Yang…·Ross L. Levine
This study identifies TET2-mutant clonal hematopoiesis in thyroid cancer microenvironments and shows that TGFβ signaling from these macrophages mediates resistance to BRAF/MEK inhibition, with TGFβ inhibition restoring sensitivity.
Gaspare La Rocca, Bryan King, Bing Shui…·Andrea Ventura
This study develops a genetic tool to reversibly inhibit miRNA-mediated gene repression in vivo and shows tissue-specific dependencies on miRNA function for homeostasis and regeneration.
Kirthi C. Reddy, Tal Dror, Jessica N. Sowa…·Emily R. Troemel
This study identifies a novel pathway, the Intracellular Pathogen Response (IPR), that promotes proteostasis in C. elegans by upregulating ubiquitin ligase components like cul-6, with pals-22 acting as a repressor.