Author

Kieran McCafferty

Queen Mary University of LondonORCID 0000-0002-0762-2270Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Muhammad Magdi YaqoobiD· 2 shared Abhishek KumariD· 1 shared Andrew V. StachulskiiD· 1 shared Christoph ThiemermanniD· 1 shared David VauzouriD· 1 shared David W. Randall· 1 shared Egle SolitoiD· 1 shared Emily ConnelliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Muhammad Magdi YaqoobORCID

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2 papers

Recent·Most cited

Artesunate Alleviate Kidney Fibrosis by Restoring Klotho Protein and Suppressing Wnt/β-Catenin Signalling Pathway

Goran Hamid Mohammad, Julius E. Kieswich, Abhishek Kumar, Kieran McCafferty, Ramyangshu Chakraborty, Christoph Thiemermann, Magdi M. Yaqoob

This study shows artesunate reduces kidney fibrosis by restoring Klotho protein and inhibiting the Wnt/β-catenin pathway in both mouse and human models.

Frontiers in Cell and Developmental Biology · Nov 13, 2025Peer-reviewedBiochemistry

Cerebrovascular damage caused by the gut microbe-derived uraemic toxin p-cresol sulfate isprevented by blockade of the epidermal growth factor receptor

Sita Shah, Tobias B-A. Knausenberger, Matthew G. Pontifex, Emily Connell, Gwénaëlle Le Gall, Tom A. J. Hardy, David W. Randall, Kieran McCafferty, Muhammad Magdi Yaqoob, Egle Solito, Michael M. Müller, Andrew V. Stachulski, Robert Charles Glen, David Vauzour, Lesley Hoyles, Simon McArthur

This study shows p-cresol sulfate impairs the blood-brain barrier via EGFR activation and demonstrates EGFR blockade prevents this damage in vitro.

Gut Microbes · Nov 24, 2024Peer-reviewedSystems Biology