Virginija Cvirkaitė‐Krupovič

Molecular architecture of colossal surface layers from hyperthermophilic archaea

This study determines the structure of a large S-layer protein from Pyrobaculum arsenaticum using cryo-EM and AlphaFold, revealing its unique multidomain architecture and evolutionary conservation.

Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes

This study analyzes the cell cycle of Saccharolobus islandicus and finds that transcriptional patterns are conserved with eukaryotes, showing phase-specific gene expression for metabolism, protein synthesis, and chromatinization.

Biogenesis of DNA-carrying extracellular vesicles by the dominant human gut methanogenic archaeon

This study characterizes DNA-carrying extracellular vesicles (EVs) from Methanobrevibacter smithii, revealing their role in DNA and protein export in the gut.