Author
University Medical Center GroningenORCID 0000-0002-8966-8466Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Marleen van der Laan, Sam Verwimp, Oleta T. Johnson…·Jolanda M. Smit
This study shows that inhibiting Hsp70 reduces chikungunya virus infectious particle production without harming host cells.
Tessa Bergsma, Maiara Kolbe Musskopf, Alejandro Feito…·Liesbeth M. Veenhoff
The paper shows that DNAJB6's conserved intrinsically disordered region enables its surveillance of FG-Nup condensates by forming stable assemblies that outcompete FG-Nup interactions.
E. F. Elsiena Kuiper, Paola Gallardo, Tessa Bergsma…·Steven Bergink
This study identifies DNAJB6 as a molecular chaperone that prevents FG-Nup aggregation during interphase nuclear pore complex biogenesis.
Wouter Huiting, Suzanne L. Dekker, Joris CJ van der Lienden…·Steven Bergink
The paper shows that targeting ATM, ATR, or DNA topoisomerases causes widespread protein aggregation through chaperone system overload, similar to proteotoxic stress and proteinopathies.
Wouter Huiting, Alejandra Duque‐Jaramillo, Renée I. Seinstra…·Steven Bergink
This study shows that defects in DDR pathways in C. elegans lead to protein homeostasis loss, which can be rescued by HSP-16.2, preventing motor impairment.
Eliana Nachman, Anne S. Wentink, Karine Madiona…·Carmen I. Nussbaum-Krammer
This study shows that the Hsp70 disaggregation machinery disassembles Tau fibrils, generating small seeding-competent Tau species that can drive aggregation.