Author

Kelsey Temprine

University of MichiganORCID 0000-0002-1322-6450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Costas Andreas LyssiotisiD· 2 shared Yatrik Madhukar ShahiD· 2 shared Aaron D. denDekkeriD· 1 shared Amanda D. Sankar· 1 shared Arjun Jha· 1 shared Christopher Mays· 1 shared Cristina CastilloiD· 1 shared Dominik AwadiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Costas Andreas LyssiotisORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Aspartate transaminases are required for blood development

Narges Pourmandi, Greggory Myers, Arjun Jha, Kelsey Temprine, Amanda D. Sankar, Nupur Kanti Das, Ridwana Khan, Siva Kumar Natarajan, Cristina Castillo, Peter Sajjakulnukit, Noah S. Nelson, Matthew D. Perricone, Indrani Talukder, Aaron D. denDekker, Lin Lin, , Costas Andreas Lyssiotis

This study identifies aspartate transaminases GOT1 and GOT2 as critical for erythropoiesis by linking metabolism to epigenetic regulation, revealing a novel role in blood development.

bioRxiv · Sep 16, 2025 · PreprintBiochemistry

Glucose Metabolism Sustains Aberrant STAT3 Signaling in Colorectal Cancer via Glycosylated Paracrine Factors.

Kathryn Buscher, Kelsey Temprine, Christopher Mays, Noora Aabed, Samuel A. Kerk, Hannah Noelle Bell, Joseph A. Nieto Carrion, Harrison S. Greenbaum, Varun Ponnusamy, Sadeesh Kumar Ramakrishnan, Costas Andreas Lyssiotis, Xiang Xue, Yatrik Madhukar Shah

This study shows glucose metabolism sustains STAT3 activation in colorectal cancer through glycosylated paracrine factors, identifying a potential therapeutic target.

bioRxiv · Jul 22, 2025 · PreprintCancer Biology