Author

Marion Larroque

Centre National de la Recherche ScientifiqueORCID 0000-0002-1384-7302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra FauvreiD· 1 shared Céline GongoraiD· 1 shared Charlotte GrimaudiD· 1 shared Christian LarroqueiD· 1 shared Corinne HenriquetiD· 1 shared Cyril RibeyreiD· 1 shared David LlèresiD· 1 shared Emilie Renaud· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Alexandra FauvreORCID

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2 papers

Recent·Most cited

Characterization of the p38α MAPK allosteric inhibition by a single chain Fv antibody

Emilie Renaud, Marion Larroque, Nicole Bec, Hugo Guérin, Raphaël Sierocki, Corinne Henriquet, Martine Pugnière, Oriane Font, Alexandra Fauvre, Vincent Denis, Céline Gongora, Christian Larroque, Pierre Martineau, Laurence Guglielmi

This paper identifies a single-chain Fv antibody that allosterically inhibits p38α MAPK by binding to a site distinct from the ATP-binding pocket, reducing inflammation in THP-1 cells.

bioRxiv · Jan 6, 2026 · PreprintBiochemistry

Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8

Yannick Perez, Fatima Alhourani, Julie Patouillard, Cyril Ribeyre, Marion Larroque, Véronique Baldin, David Llères, Charlotte Grimaud, Eric Julien

This study shows SET8 inhibits BRCA1 signaling during S-phase by promoting 53BP1 accumulation, and its degradation is essential for BRCA1 and RAD51 complex nuclear focal accumulation.

Cell Cycle · Feb 16, 2025Peer-reviewedMolecular Biology