Author

Vincent Denis

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Laurence GuglielmiiD· 2 shared Pierre MartineauiD· 2 shared Alexandra FauvreiD· 1 shared Annabel LarnicoliD· 1 shared Céline GongoraiD· 1 shared Charlotte SarreiD· 1 shared Christian LarroqueiD· 1 shared Corinne HenriquetiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Laurence GuglielmiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Selective targeting of RalA with intrabodies impairs Triple Negative Breast Cancer metastasis

Charlotte Sarre, Kateřina Jeřábková, Vincent Denis, Giulia Bertolin, Marc Tramier, Louis Bochler, Cristina Liboni, Ignacio Busnelli, Quentin Frenger, Annabel Larnicol, Frédéric Gros, Olivier Lefèbvre, Laurence Guglielmi, Jacky G. Goetz, Vincent Hyenne, Pierre Martineau

This paper develops RalA-specific intrabodies that inhibit mitochondrial fission and extracellular vesicle secretion, reducing metastasis in a TNBC mouse model.

bioRxiv · Jan 9, 2026 · PreprintCancer Biology

Characterization of the p38α MAPK allosteric inhibition by a single chain Fv antibody

Emilie Renaud, Marion Larroque, Nicole Bec, Hugo Guérin, Raphaël Sierocki, Corinne Henriquet, Martine Pugnière, Oriane Font, Alexandra Fauvre, Vincent Denis, Céline Gongora, Christian Larroque, Pierre Martineau, Laurence Guglielmi

This paper identifies a single-chain Fv antibody that allosterically inhibits p38α MAPK by binding to a site distinct from the ATP-binding pocket, reducing inflammation in THP-1 cells.

bioRxiv · Jan 6, 2026 · PreprintBiochemistry