Rifat Hamoudi

Cooperative Modular Representation Learning for Lung Adenocarcinoma Survival Prediction from Transcriptomic and Clinical Data

This paper introduces CMRL, a multimodal framework for LUAD survival prediction that integrates transcriptomic and clinical data, achieving better performance than existing methods.

Discovery of a Systemic Immune-Inflammatory Axis Bridging the Neuroendocrine System and Breast Tumor Microenvironment via MMD-Regularized Cross-Tissue Latent Alignment

This paper identifies a systemic immune-inflammatory axis linking neuroendocrine regulation and breast tumor microenvironment using cross-tissue latent alignment of transcriptomic data.

A Systems Biology Approach to Unveil Shared Therapeutic Targets and Pathological Pathways Across Major Human Cancers

This study identifies 26 hub genes shared across breast, lung, colorectal, and prostate cancers using RNA-seq data from TCGA, highlighting their potential as therapeutic targets and prognostic markers.

The Emirati T2T-Level Pangenome: A Graph of 58 Complete Genomes

The paper presents a T2T-level pangenome of 58 Emirati genomes, revealing genomic diversity comparable to the Human Pangenome Reference Consortium.

Deciphering Neuronal Deficit and Protein Profile Changes in Human Brain Organoids from Patients with Creatine Transporter Deficiency

This study uses human brain organoids to show that restoring SLC6A8 function in CTD patients normalizes protein expression and creatine uptake, suggesting potential therapeutic targets for CTD.

Dodecyl Creatine Ester Improves Cognitive Function and Identifies Drivers of Creatine Deficiency.

The paper identifies 14 biomarkers associated with cognitive improvement in a Slc6a8 knockout mouse model treated with DCE, linking them to proteins involved in CTD pathogenesis.

Multiple early introductions of SARS-CoV-2 into a global travel hub in the Middle East

The paper analyzes SARS-CoV-2 genome sequences from Dubai to show multiple introductions from Asia, Europe, and the Middle East during the early pandemic and identifies new mutations.

The Personal Genome Project-UK: an open access resource of human multi-omics data

The paper describes the PGP-UK multi-omics reference panel, providing open access to genomic, methylomic, and transcriptomic data with quality control and API access.

PGP-UK: a research and citizen science hybrid project in support of personalized medicine

PGP-UK explores citizen science in genomics by recruiting participants, sharing data, and developing tools to advance personalized medicine.

DNA methylation oscillation defines classes of enhancers

The paper identifies DNA methylation oscillations as a marker for enhancer classification, showing high predictive power compared to other methods.