Author

Carina Seidl

German Cancer Research CenterORCID 0000-0002-1562-8453Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1 Organism:Xenopus· 1

Frequent Co-Authors

Christof NiehrsiD· 2 shared Alena IvanovaiD· 1 shared Andrey Glinka· 1 shared Bianca PokrandtiD· 1 shared Britta BrüggeriD· 1 shared Diego Aponte-Santamaria· 1 shared Dominique KranziD· 1 shared Eddye J. Figueroa Marquez· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Christof NiehrsORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 2, 2025

Secretion and signaling properties of Wnt11 and Wnt3 are determined by their N-terminus

Oksana Voloshanenko, Nachiket Dhonnar, Diego Aponte-Santamaria…·Michael Boutros

This study shows that the N-terminus of Wnt proteins determines their secretion and signaling properties, with Wnt11's N-terminus enabling Evi/Wls-independent secretion and Frizzled 6 activation.

DOI 10.1101/2025.07.02.662750

Xenopusproteomics

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Developmental BiologyNature CommunicationsPeer-reviewedNov 4, 2020

R-spondins are BMP receptor antagonists in early embryonic development

Hye-Yoon Lee, Carina Seidl, Rui Sun…·Christof Niehrs

This study identifies R-spondins as BMP receptor antagonists, showing they inhibit BMP signaling via ZNRF3 and regulate dorsoventral axis formation in Xenopus embryos.

54 citations

experimental assay

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