Author

Diego Aponte-Santamaria

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1 Organism:Xenopus· 1

Frequent Co-Authors

Alena IvanovaiD· 1 shared Bianca PokrandtiD· 1 shared Britta BrüggeriD· 1 shared Carina SeidliD· 1 shared Christof NiehrsiD· 1 shared Dominique KranziD· 1 shared Eddye J. Figueroa Marquez· 1 shared Fillip PortiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alena IvanovaORCID

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1 paper

Recent·Most cited

Secretion and signaling properties of Wnt11 and Wnt3 are determined by their N-terminus

Oksana Voloshanenko, Nachiket Dhonnar, Diego Aponte-Santamaria, Carina Seidl, Lucie Wolf, Dominique Kranz, Alena Ivanova, Eddye J. Figueroa Marquez, Bianca Pokrandt, Iris Augustin, Irmgard M. Sinning, Fillip Port, Christof Niehrs, Britta Brügger, Michael Boutros

This study shows that the N-terminus of Wnt proteins determines their secretion and signaling properties, with Wnt11's N-terminus enabling Evi/Wls-independent secretion and Frizzled 6 activation.

bioRxiv · Jul 2, 2025 · PreprintCell Biology