Author

Kimberly F. Fennell

Pfizer (United States)ORCID 0000-0002-1687-5237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Huixian WuiD· 2 shared Aaron Yam· 1 shared Alexander MuikiD· 1 shared Andrew P. McKeen· 1 shared Annaliesa S. AndersoniD· 1 shared Carla Iris Cadima Couto· 1 shared Chiachin Wilson Lee· 1 shared Daiana Sharaf· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Huixian WuORCID

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2 papers

Recent·Most cited

Insight into the scaffolding function of USP18 from a high resolution cryo-EM structure of STAT2-USP18-ISG15 ternary complex

Kevin W. Huynh, Rachel Plumb, David R. Healy, Veronica Jové, Erik C. Ralph, Chiachin Wilson Lee, Heather Wheeler, Kymberly K. Levine, Zhen Huang, Kimberly F. Fennell, Richard A. Corpina, Timothy K. Craig, Paul D. Wes, Paula M. Loria, Monica Schenone, , Masaya Yamaguchi

The paper determines the structure of the STAT2-USP18-ISG15 ternary complex using cryo-EM, revealing how USP18's scaffolding function suppresses IFN-I signaling by disrupting its enzymatic activity.

bioRxiv · Feb 12, 2026 · PreprintMolecular Biology

Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines

Wei J. Chen, Kristin R. Tompkins, Ian W. Windsor, Lyndsey T. Martinez, Minah Ramos, Weiqiang Li, Shikha Shrivastava, Swati Rajput, Jeanne S. Chang, Parag V. Sahasrabudhe, Kimberly F. Fennell, Thomas J. McLellan, Graham M. West, Kristianne P. Dizon, Aaron Yam, , Kayvon Modjarrad

Omicron JN.1- and KP.2-adapted BNT162b2 mRNA vaccines elicit stronger neutralizing antibody responses against circulating sublineages than previous vaccines, supporting annual strain updates.

Nature Communications · Dec 5, 2025Peer-reviewedImmunology