David J. P. Ferguson

This study uses electron tomography to investigate basal body dynamics during microgamete formation and fertilization in Plasmodium, revealing novel structural features and their role in gamete fusion.

This study identifies PfAP2-HCR as a critical transcription factor regulating host cell remodeling in Plasmodium falciparum, essential for parasite survival and transmission.

This study identifies Plasmodium NEK4 as a key regulator that couples meiotic initiation with zygote morphogenesis in malaria parasites.

This study identifies ARK1 as a critical regulator of mitosis in Plasmodium, forming a non-canonical chromosomal passenger complex with divergent INCENPs, and highlights its potential as an antimalarial target.

This study investigates the formation of subpellicular microtubules in Toxoplasma gondii using expansion microscopy and genetic analysis, revealing their co-dependent assembly with the inner membrane skeleton.

This study identifies three Plasmodium protein kinases involved in regulating MTOC, kinetochore, and axoneme organisation during male gametogenesis, revealing their substrates and morphological effects.

This study identifies the SUN1-ALLAN complex as critical for coordinating nuclear envelope remodeling and bipartite MTOC segregation during rapid mitosis in Plasmodium male gametogenesis.

This study identifies NEK1's role in organizing the MTOC and ensuring kinetochore attachment during rapid mitosis in Plasmodium male gamete formation.

This study identifies PfAP2-MRP as a master regulator controlling parasite growth, chromatin structure, and var gene expression during malaria parasite blood stages.

This study models erythropoiesis in CDA-I by analyzing patient-derived erythroblasts, identifying abnormalities in DNA accessibility, proliferation, and enucleation, with genotype-phenotype correlations.