Author

Mohammad Zeeshan

University of NottinghamORCID 0000-0002-6185-403XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:plant (other)· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:proteomics· 3 Approach:microscopy & imaging analysis· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Declan BradyiD· 8 shared Rita TewariiD· 8 shared Anthony A. HolderiD· 7 shared Akancha MishraiD· 6 shared Andrew R. BottrilliD· 6 shared David S. GutteryiD· 5 shared Eelco C. TromeriD· 5 shared Sue VaughaniD· 5 shared

Activity by Year

2024-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

8 shared papersMicrobiology

Declan BradyORCID

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Plasmodium rootlet SFA1 coordinates cell replication, apical polarity and cytoskeletal organisation during sexual development

Declan Brady, Akancha Mishra, Philip Ilani, David J. P. Ferguson, Prince Ubiaru, Robert Markus, Andrew Bottrill, Mohammad Zeeshan, Sue Vaughan, David S. Guttery, Eelco C. Tromer, Anthony A. Holder, Rita Tewari

This study identifies SFA1's role in coordinating cytoskeletal organisation, apical polarity, and cell replication during Plasmodium sexual development, showing its necessity for parasite transmission.

bioRxiv · Nov 2, 2026 · PreprintCell Biology

A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis

Ryuji Yanase, Molly Hair, Mohammad Zeeshan, David J. P. Ferguson, Declan Brady, Carla Pasquarello, Andrew R. Bottrill, Suhani Bhanvadia, Armund Neal, Eelco C. Tromer, Karine G. Le Roch, Alexandre Hainard, Anthony A. Holder, Sue Vaughan, David S. Guttery, Rita Tewari

This study identifies Plasmodium NEK4 as a key regulator that couples meiotic initiation with zygote morphogenesis in malaria parasites.

Nature Communications · May 12, 2026Peer-reviewedMicrobiology

Plasmodium Protein Kinase 2 is required for ookinete to oocyst transition, and parasite transmission by the mosquito.

Sarah L. Pashley, Molly Hair, Chiamaka Valerie Ukegbu, Mohammad Zeeshan, Akancha Mishra, Declan Brady, Sue Vaughan, Carla Pasquarello, Anthony Holder, Alexandre Hainard, David S. Guttery, George K. Christophides, Dina Vlachou, Pushkar Sharma, Rita Tewari

This study shows that Plasmodium Protein Kinase 2 is essential for the ookinete to oocyst transition and sporozoite development in the mosquito, affecting parasite transmission.

bioRxiv · Apr 2, 2026 · PreprintMicrobiology

GAPMs form a heterotrimeric complex bridging the gliding machinery and the cytoskeleton across Plasmodium species

Akancha Mishra, Giedrė Ratkevičiūtė, Amy Ibrahim, Dušan Živković, Mohammad Zeeshan, Declan Brady, Andrew R. Bottrill, Jani Reddy Bolla, Eelco C. Tromer, Robert William Moon, Rita Tewari, Clinton K. Lau

The paper identifies GAPM2 as an IMC component in Plasmodium species and reveals its heterotrimeric complex structure and functional role in the glideosome.

bioRxiv · Mar 27, 2026 · PreprintMicrobiology

Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex

Annu Nagar, Ryuji Yanase, Mohammad Zeeshan, David J. P. Ferguson, Steven Abel, Sarah L. Pashley, Akancha Mishra, Anthonius Anayochukwu Eze, Edward Rea, Declan Brady, Andrew R. Bottrill, Sue Vaughan, Karine G. Le Roch, David S. Guttery, Anthony A. Holder, , Rita Tewari

This study identifies ARK1 as a critical regulator of mitosis in Plasmodium, forming a non-canonical chromosomal passenger complex with divergent INCENPs, and highlights its potential as an antimalarial target.

Nature Communications · Feb 26, 2026Peer-reviewedMicrobiology

Apicortin defines the Plasmodium apical conoid body during transmission but is dispensable for the parasite life cycle

Mohammad Zeeshan, Akancha Mishra, Sarah L. Pashley, Róbert Márkus, Declan Brady, Anthony A. Holder, Carolyn Ann Moores, Rita Tewari

This study shows Apicortin is localized to the apical conoid body of Plasmodium berghei during transmission but is not essential for parasite development or transmission.

bioRxiv · Oct 1, 2025 · PreprintCell Biology

Divergent Plasmodium protein kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis

Ryuji Yanase, Mohammad Zeeshan, David J. P. Ferguson, Róbert Márkus, Declan Brady, Andrew R. Bottrill, Anthony A. Holder, David S. Guttery, Rita Tewari

This study identifies three Plasmodium protein kinases involved in regulating MTOC, kinetochore, and axoneme organisation during male gametogenesis, revealing their substrates and morphological effects.

Life Science Alliance · Mar 24, 2025Peer-reviewedMicrobiology

A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium

Mohammad Zeeshan, Igor Blatov, Ryuji Yanase, David J. P. Ferguson, Sarah L. Pashley, Zeinab M Chahine, Yoshiki Yamaryo‐Botté, Akancha Mishra, Baptiste Marché, Suhani Bhanvadia, Molly Hair, Sagar Batra, Róbert Márkus, Declan Brady, Andrew R. Bottrill, , Rita Tewari

This study identifies the SUN1-ALLAN complex as critical for coordinating nuclear envelope remodeling and bipartite MTOC segregation during rapid mitosis in Plasmodium male gametogenesis.

bioRxiv · Dec 4, 2024Cell Biology