Author

Steven Vitale

University of PennsylvaniaORCID 0000-0002-1802-759XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hongbo LiuiD· 2 shared Katalin SusztákiD· 2 shared Matthew PalmeriD· 2 shared Steven S. PulleniD· 2 shared Ziyuan MaiD· 2 shared Adriana M. HungiD· 1 shared Amin AbediniiD· 1 shared Anil K. KarihalooiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetics

Hongbo LiuORCID

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2 papers

Recent·Most cited

Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression

Amin Abedini, Jonathan L. Levinsohn, Konstantin A. Klötzer, Bernhard Dumoulin, Ziyuan Ma, Julia Frederick, Poonam Dhillon, Michael S. Balzer, Rojesh Shrestha, Hongbo Liu, Steven Vitale, Kishor B. Devalaraja-Narashimha, Paola Grandi, Tanmoy Bhattacharyya, Erding Hu, , Katalin Suszták

Multi-omic and spatial profiling of 81 human kidney samples resolves four tissue microenvironments; the fibrotic one's gene signature is reported to beat histopathology at predicting outcome.

bioRxiv · Oct 24, 2022 · PreprintGenetics

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, , Katalin Suszták

The paper maps genetic variants to cell types in the kidney to identify disease mechanisms and drug targets.

Nature Genetics · Aug 12, 2021Peer-reviewedGenetics