Reed McMullen

Developmental signaling reveals functionally enriched human-specific gene regulation in telencephalic progenitors

The paper identifies human-specific gene regulation in telencephalic progenitors by analyzing morphogen-dependent gene expression responses across human, chimpanzee, and orangutan species.

NPEPPS segmental duplication drives position effect expression of TBC1D3 in the human brain

The paper identifies a segmental duplication that drives position effect expression of TBC1D3 in the human brain, explaining its high structural heterozygosity.

ANTIPODE Provides a Global View of Cell Type Homology and Transcriptomic Divergence in the Developing Mammalian Brain

ANTIPODE integrates single-cell data across species to identify homologous cell types and reveal gene regulatory divergence in developing mammalian brains.

Interspecies Organoids Reveal Human-Specific Molecular Features of Dopaminergic Neuron Development and Vulnerability