Janko Kajtez

This paper describes a method to generate dense neuronal microcultures by combining fibroblast reprogramming with matrix remodeling in collagen microgels.

The paper introduces a human stem cell-based model of the nigrostriatal pathway that mimics in vivo connectivity and reveals target-dependent dopamine neuron maturation.

This study generates human appetite-regulating neurons and tanycytes from stem cells, identifying key progenitor markers and signaling mechanisms for hypothalamic subregion specification.

This study investigates how co-grafting strategies influence dopamine neuron specification and maturation in a Parkinson's disease model, identifying key transcription factors involved in the process.

This study shows human neurons reprogrammed from glial progenitor cells survive and mature functionally in immunodeficient mice for up to 10 months.

This study develops a 3D microculture method to generate mature dopamine neurons from patient fibroblasts, which can be transplanted into a Parkinson's disease rat model to form functional neuron grafts.

The paper uses a microfluidic stem cell model to study early human neural patterning, identifying regional specification and fate determination during the epiblast stage.

The paper uses single-cell RNA sequencing to profile fetal human midbrain dopamine neurons at different developmental stages and establishes a 3D culture system to study their functional maturation.