Vanessa Linke

Integrated proteome and lipidome analyses place OCIAD1 at mitochondria-peroxisome intersection balancing lipid metabolism

The paper uses proteomics and lipidomics to show OCIAD1 balances mitochondrial and peroxisomal lipid metabolism by affecting lipid composition and key enzymes.

OMA1 protease eliminates arrested protein import intermediates upon depolarization of the inner mitochondrial membrane.

The paper identifies OMA1 protease as a key factor in resolving arrested protein import intermediates in human cells through mitochondrial membrane depolarization.

Systems genetics uncovers microbe-lipid-host connections in the murine gut

This study identifies genetic links between gut microbiota, lipids, and host transcripts in mice, revealing key roles for Akkermansia muciniphila and ornithine lipids in microbe-host interactions.

Genetic determinants of gut microbiota composition and bile acid profiles in mice

This study identifies genetic loci associated with gut microbiota composition and bile acid profiles in mice using QTL analysis and validation experiments.