Stefan Kol

This study eliminates the Warburg Effect in mammalian cells by knocking out lactate dehydrogenase and feedback regulators, maintaining growth rate while reducing lactate production.

The paper identifies protein-protein interactions supporting recombinant protein secretion using BioID and Bayesian modeling, finding key roles for oxidative folding enzymes in disulfide bond formation.

This paper describes a method to evolve and functionalize biosensors in yeast by optimizing ligand specificity and transfer functions through directed evolution.