Author

Audrey Labarre

Centre Hospitalier de l’Université de MontréalORCID 0000-0002-2167-2290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

J. Alex ParkeriD· 3 shared Claudia MaiosiD· 2 shared Alexandre EmondiD· 1 shared Alisa HuiiD· 1 shared Anthony BossoniD· 1 shared Baptiste LacosteiD· 1 shared Benjamin Rogers· 1 shared Carl LaflammeiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

J. Alex ParkerORCID

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3 papers

Recent·Most cited

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis

Romane Manceau, Celena M. Cherian, Danie Majeur, Colin J. Miller, Jasper D. Fisher, Frédérick Boisjoly, J. Beatrice Liston, Jennifer A. Bako, Lianna W. Wat, Charlotte F. Chao, Audrey Labarre, Serena Hollman, Sanjana Prakash, Sébastien Audet, Lewis R Depaauw-Holt, , Thierry Alquier

The paper identifies neuronal lipid droplets as conserved structures that regulate energy homeostasis with sex-biased effects in flies and mice.

Nature Metabolism · Apr 14, 2026Peer-reviewedNeuroscience

Characterization of a C9orf72 Knockout Danio rerio model for ALS and cross-species validation of potential therapeutics screened in Caenorhabditis elegans.

Alexandre Emond, Carl Laflamme, Martine Therrien, Meijiang Liao, Claudia Maios, Audrey Labarre, Pierre Drapeau, J. Alex Parker

The paper develops a zebrafish C9orf72 knockout model for ALS, identifies pizotifen malate as a potential therapeutic, and validates its efficacy in both zebrafish and C. elegans models.

PLoS ONE · Apr 10, 2026Peer-reviewedGenetics

Mimicking of tau hyperphosphorylation in GABAergic motoneurons of C. elegans induces severe peripheral and neuronal alterations

Audrey Labarre, Emilien Schramm, Julie Pilliod, Samuel Boyer, Marianne Lapointe, Claudia Maios, Nicole M. Leclerc, J. Alex Parker

This study shows that overexpressing tau variants in C. elegans motor neurons causes neuronal and peripheral defects, suggesting tau dysfunction disrupts cell-cell communication.

bioRxiv · Jul 4, 2023 · PreprintNeuroscience