Alberto Bacci

Alterations of adult prefrontal circuits induced by early postnatal fluoxetine treatment mediated by 5-HT7 receptors.

This study shows that early postnatal fluoxetine exposure alters adult prefrontal cortex circuits via 5-HT7 receptors, affecting neuronal firing patterns and contributing to depressive and anxiety-like behaviors.

A dendritic substrate for temporal diversity of cortical inhibition

The paper identifies distinct dendritic integration strategies in two types of cortical interneurons that lead to different temporal dynamics of inhibition.

An unconventional GABAergic circuit differently controls pyramidal neuron activity in two visual cortical areas via endocannabinoids

The paper identifies a differential role of CB1-expressing interneurons in controlling pyramidal neuron activity in primary and secondary visual cortical areas through distinct endocannabinoid mechanisms.

Molecular signature and target-specificity of inhibitory circuits formed by Martinotti cells in the mouse barrel cortex

The paper identifies the molecular signature and connectivity specificity of Martinotti cell inhibitory circuits in the mouse barrel cortex, revealing target-specific synaptic properties and the role of 5-GABAARs in cognitive functions.

Alterations of specific inhibitory circuits of the prefrontal cortex underlie abnormal network activity in a mouse model of Down syndrome

The paper identifies specific inhibitory circuit alterations in the prefrontal cortex of a Down syndrome mouse model, linking them to cognitive dysfunction.

Modulation of coordinated activity across cortical layers by plasticity of inhibitory synapses onto layer 5 pyramidal neurons

The paper shows that plasticity of inhibitory synapses onto layer 5 pyramidal neurons modulates excitation-inhibition ratios, neuronal gain, and information transfer across cortical layers.

Strong preference for autaptic self-connectivity of neocortical PV interneurons entrains them to γ-oscillations

The paper investigates autaptic self-connectivity in neocortical PV interneurons and finds it significantly contributes to perisomatic inhibition and synchronization with gamma-oscillations.

Perineuronal nets set the strength of thalamic recruitment of interneurons in the adult visual cortex

This study shows that perineuronal nets (PNNs) in the adult mouse visual cortex regulate thalamic recruitment of PV interneurons, affecting visual processing and plasticity.