Author

Pierre Khneisser

InsermORCID 0000-0002-2422-2121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Antonin MarchaisiD· 2 shared Birgit GeoergeriD· 2 shared Maria Eugénia Marques Da CostaiD· 2 shared Nathalie GaspariD· 2 shared Baptiste Audinot· 1 shared Bruno FigadèreiD· 1 shared Catherine BrenneriD· 1 shared Corentin ThuillieziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPharmacology & Toxicology

Antonin MarchaisORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Engineered flavonoid disrupts mitochondrial AIF/CHCHD4 complex for targeted cancer therapy

Hong-Toan Lai, Daniela Dias‐Pedroso, Maria Eugénia Marques Da Costa, Romain Fernandes, Tran Ngoc Anh Nguyen, Olivia Bawa, Pierre Khneisser, João Gabriel Silva, Yassine Khalij, Michelangelo Campanella, John Griffith Jones, Svetlana Dokudovskaya, Guido Kroemer, Antonin Marchais, Nathalie Gaspar, , Catherine Brenner

This paper identifies M30-E05, an engineered flavonoid that disrupts the AIF/CHCHD4 mitochondrial complex, reducing cancer cell viability and tumor growth in xenograft models.

Acta Pharmaceutica Sinica B · Jun 15, 2026Peer-reviewedPharmacology & Toxicology

CellsFromSpace: A fast, accurate and reference-free tool to deconvolve and annotate spatially distributed Omics data

Corentin Thuilliez, Gaël Moquin‐Beaudry, Pierre Khneisser, Maria Eugénia Marques Da Costa, Slim Karkar, Hanane Boudhouche, Damien Drubay, Baptiste Audinot, Birgit Geoerger, Jean‐Yves Scoazec, Nathalie Gaspar, Antonin Marchais

CellsFromSpace is a reference-free tool for deconvolving and annotating spatial transcriptomic data, outperforming existing methods in accuracy and speed across multiple technologies.

Bioinformatics Advances · Jan 1, 2024Peer-reviewedBioinformatics