Charles Fieseler

Flexible modulation of neuronal population dynamics drives variable decision-making in C. elegans

The paper shows that decision-making variability in C. elegans arises from slow modulation of brain states rather than random noise, using calcium imaging and optogenetics.

BarlowTrack: A Self-Supervised Framework for Zero-Shot Multi-Object Cell Tracking

This paper introduces BarlowTrack, a self-supervised cell tracking framework that achieves zero-shot accuracy across conditions and labs for neuronal time series in C. elegans.

Cerebral Organoids Uncover Mechanisms of Neural Activity Changes in Epileptogenesis

This paper uses cerebral organoids to model Tuberous Sclerosis Complex and identifies mechanisms of neural activity changes in epileptogenesis, showing potential for drug testing.

An intrinsic neuronal manifold underlies brain-wide hierarchical organization of behavior in C. elegans

The paper identifies an intrinsic neuronal manifold in C. elegans that underlies brain-wide hierarchical organization of behavior by gating neuron activity during specific brain states.