Hope G. Kronman

This study identifies a novel epigenetic mechanism by which chronic cocaine exposure alters gene expression in nucleus accumbens neurons through H2A.Z depletion and chromatin changes.

This study identifies H3K27me1 as a chromatin scar that mediates lifelong stress susceptibility through its role in altering gene expression in the nucleus accumbens.

This study shows that early life stress alters transcriptomic patterns in reward circuitry of male and female mice, increasing sensitivity to adult stress.

The paper compares RNAseq methods for analyzing medium spiny neurons in the nucleus accumbens, finding that nuclear-FACS-seq identifies more differentially expressed genes and GWAS hits than other methods.