Angélica Torres‐Berrío

Transcriptional Profiles of Antidepressant Resistance Across the Corticolimbic Pathway of Chronically Stressed Mice

This study identifies transcriptional differences in mice with antidepressant resistance using RNA sequencing of brain regions after stress and drug treatment.

Sex-Specific Induction of H3K27me1 in the Prefrontal Cortex Mediates the Enduring Effects of Early Life Stress

This study shows that early life stress causes sex-specific H3K27me1 accumulation in the prefrontal cortex, leading to long-term behavioral and cognitive effects in mice.

Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens

This study shows that E2F3a overexpression in D1-MSNs increases cocaine reward in both male and female mice, while knockdown has opposite effects, with no impact in D2-MSNs.

Monomethylation of Lysine 27 at Histone 3 Confers Lifelong Susceptibility to Stress

This study identifies H3K27me1 as a chromatin scar that mediates lifelong stress susceptibility through its role in altering gene expression in the nucleus accumbens.

Sex-Specific Regulation of Stress Susceptibility by the Astrocytic Gene Htra1

The paper identifies sex-specific regulation of stress susceptibility by the astrocytic gene Htra1 in mice and humans, showing differential effects on neuronal signaling and ECM integrity.

Transcriptional signatures of heroin intake and seeking throughout the brain reward circuit

This study identifies transcriptional changes in the brain reward circuit across heroin exposure and seeking behaviors in mice, revealing molecular mechanisms and potential therapeutic targets for opioid use disorder.

The Long Noncoding RNA FEDORA is a Cell-Type- and Sex-Specific Regulator of Depression

The paper identifies FEDORA, a lncRNA with sex- and cell-type-specific effects on depression in females.

miR-218 in adolescence predicts and mediates vulnerability to stress

This study shows that miR-218 expression in adolescence predicts and mediates vulnerability to stress in adulthood by regulating Dcc expression in the medial prefrontal cortex.

Adolescent Social Isolation Reprograms the Medial Amygdala: Transcriptome and Sex Differences in Reward

The paper shows that adolescent social isolation causes sex-specific changes in the medial amygdala's transcriptome and behavior, with Crym playing a key role in these effects.

MiR-218: A Molecular Switch and Potential Biomarker of Susceptibility to Stress

This study shows that miR-218 in the medial prefrontal cortex (mPFC) influences resilience or susceptibility to depression-like behaviors in mice and that its expression in blood correlates with mPFC levels.