Yentl Y. van der Zee

This study identifies a novel epigenetic mechanism by which chronic cocaine exposure alters gene expression in nucleus accumbens neurons through H2A.Z depletion and chromatin changes.

This study identifies H3K27me1 as a chromatin scar that mediates lifelong stress susceptibility through its role in altering gene expression in the nucleus accumbens.

The paper identifies sex-specific regulation of stress susceptibility by the astrocytic gene Htra1 in mice and humans, showing differential effects on neuronal signaling and ECM integrity.

The paper investigates genetic and sex differences in stress and morphine responses across mouse strains and their progeny, finding genetic influences on stress vulnerability and morphine sensitivity.

The paper identifies FEDORA, a lncRNA with sex- and cell-type-specific effects on depression in females.

The paper shows that adolescent social isolation causes sex-specific changes in the medial amygdala's transcriptome and behavior, with Crym playing a key role in these effects.