KMT2E recruitment by H3 serotonylation regulates neurodevelopmental chromatin dynamics
Jennifer C. O’Chan, Benjamin H. Weekley, Celi Yang, Min Chen, Ashley M. Cunningham, Sohini Dutta, Winnie Chen, Rasika R. Iyer, Newaz I. Ahmed, Bulent Cetin, Cari A. Sagum, Bradley J. Lukasak, Erdene Baljinnyam, Zoé Christenson Wick, Vishwendra Patel, , Ian S. Maze
This study identifies KMT2E as a reader of H3K4me3Q5ser, showing its role in regulating chromatin dynamics and neurodevelopmental gene expression in ODLURO syndrome.
bioRxiv · Sep 22, 2026 · PreprintNeuroscience