Author

Venu Gopal Pillarisetty

University of WashingtonORCID 0000-0002-1162-9643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Manabu NukayaiD· 2 shared Sean M. Ronnekleiv‐KellyiD· 2 shared Adrian J. McNairniD· 1 shared Alaa R. FarghliiD· 1 shared Alex C. VeithiD· 1 shared Andreas StephanouiD· 1 shared Anthony J. VeltriiD· 1 shared Austin Stram· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Manabu NukayaORCID

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Author profile →

3 papers

Recent·Most cited

The DNAJB1-PRKACA Oncogenic Fusion Drives Stepwise Biliary and Pancreatic Carcinogenesis from Intraductal Precursor Lesions

Patrick R. Carney, Manabu Nukaya, Jason A. Carter, Anthony J. Veltri, Kristina A. Matkowskyj, Austin Stram, Clifford Dustin Rubinstein, Alex C. Veith, Venu Gopal Pillarisetty, Christopher A. Bradfield, Sean M. Ronnekleiv‐Kelly

This study develops a mouse model of DNAJB1-PRKACA fusion and shows it drives biliary and pancreatic carcinogenesis, with pre-invasive features and Slc16a14 as a biomarker for malignant transformation.

bioRxiv · May 27, 2026 · PreprintCancer Biology

Single-cell multi-omic analysis of fibrolamellar carcinoma reveals rewired cell-to-cell communication patterns and unique vulnerabilities

Alaa R. Farghli, Marina Chan, Marc Samuel Sherman, Lindsay K. Dickerson, Bo Shui, Manabu Nukaya, Andreas Stephanou, Rosanna K. Ma, Brian J. Pepe-Mooney, Colton J. Smith, Donald Long, Paul R. Munn, Adrian J. McNairn, Jennifer K. Grenier, Michael Karski, , Praveen Sethupathy

This study uses single-nucleus multi-omics to analyze fibrolamellar carcinoma, revealing rewired cell communication and potential therapeutic targets.

bioRxiv · Dec 11, 2024 · PreprintCancer Biology

Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma

Xiaofei Zhang, Ruoxin Lan, Yongjun Liu, Venu Gopal Pillarisetty, Danting Li, Chaohui L Zhao, Suparna A. Sarkar, Weiguo Liu, Iman T. Hanna, Mala R. Gupta, Cristina H Hajdu, Jonathan Melamed, Jessica L. Widmer, John Allendorf, Yaozhong Liu

This study shows neoadjuvant therapy in PDAC increases complement gene expression in the tumor microenvironment, linked to better survival and reduced immune exhaustion.

bioRxiv · Oct 26, 2023 · PreprintCancer Biology