Katharine A. Michie

Viruses, Proviruses and Satellites from Asgard Archaea Enrichments Reveal Complex Microbial Interactions

The paper identifies viruses and proviruses associated with Asgard archaea and reveals virus-mediated interactions with bacteria, expanding understanding of microbial symbiosis in eukaryogenesis.

The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking

This study identifies bacterial and archaeal ancestors of eukaryotic COMMD proteins through structural and phylogenetic analysis, showing their origin from a single bacterial gene.

An Asgard archaeon from a modern analog of ancient microbial mats

The paper describes a novel Asgard archaeon and its syntrophic interaction with a sulfate-reducing bacterium, suggesting insights into early eukaryotic symbiosis.

LMI4Boltz: Optimising VRAM utilisation to predict large macromolecular complexes with consumer grade hardware

LMI4Boltz optimizes VRAM usage to predict large macromolecular complexes on consumer-grade hardware without sacrificing accuracy.

Cell division protein A (CdpA) organises and anchors the division ring at midcell in haloarchaea

This study identifies CdpA as a protein involved in organizing and anchoring the division ring in Haloferax volcanii, showing its role in stabilizing FtsZ proteins during cell division.

Systematic screens for fertility genes essential for malaria parasite transmission reveal conserved aspects of sex in a divergent eukaryote

The paper identifies 401 sex and transmission-related gene functions in malaria parasites through genetic screens, revealing conserved fertility mechanisms across eukaryotes.

Assessing the Validity of Leucine Zipper Constructs Predicted in AlphaFold2.

This study evaluates AlphaFold2 and AlphaFold-Multimer's ability to predict leucine zipper dimer interfaces in AP-1 transcription factors, revealing high confidence but potential inaccuracies.

Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in MDS/AML

This study identifies a synergy between hypomethylating agents and SUMOylation blockade in MDS/AML using CRISPR-Cas9 screening, showing improved therapeutic outcomes in xenograft models.

Molecular dissection of the soluble photosynthetic antenna from a cryptophyte alga

The paper investigates the structure and function of the photosynthetic antenna in cryptophyte algae, identifying distinct phycobiliprotein forms and their role in energy transfer.