Author

David Achudhan

Mayo ClinicORCID 0000-0002-2917-0578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abhishek ChandraiD· 2 shared Robert J. PignoloiD· 2 shared Sundeep KhoslaiD· 2 shared Aqsa Komel· 1 shared David Monroe· 1 shared Jacob J. OrmeiD· 1 shared Khubaib Gul Khan· 1 shared Ling QiniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Abhishek ChandraORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Bone and Mineral ResearchPeer-reviewedAug 7, 2026

Suppression of early pro-inflammatory senescent signature post-radiotherapy mitigates chronic bone damage

David Achudhan, Jacob J. Orme, Ritika Sharma…·Abhishek Chandra

This study shows that early suppression of the pro-inflammatory senescent secretome (SASP) with ruxolitinib reduces chronic bone damage after radiotherapy.

DOI 10.1093/jbmr/zjag122

mousehuman

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GenomicsCalcified Tissue InternationalPeer-reviewedMay 25, 2026

MicroRNA Networks Driving Skeletal Aging and WNT Pathway Modulation

David Achudhan, David Monroe, Mrunal K. Dehankar…·Abhishek Chandra

The paper identifies common differentially regulated microRNAs in skeletal aging and radiation-induced bone deterioration, linking them to WNT pathway modulation and senescence.

DOI 10.1007/s00223-026-01549-z

mousestatistical model

𝕏 PostBluesky