Toan K. Phung

Data-independent acquisition (DIA) approach for comprehensive ubiquitinome profiling in targeted protein degradation

This study develops a DIA-based workflow for comprehensive ubiquitinome profiling in targeted protein degradation, identifying over 40,000 ubiquitylated peptides.

CURTAIN - A Unique Web-based tool for exploration and sharing of MS-based proteomics data

CURTAIN and CURTAIN-PTM are web-based tools for exploring and sharing MS-based proteomics data, enabling non-experts to analyze and visualize results through interactive features and shareable links.

Parkinsons VPS35 mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B

This study shows that the VPS35[D620N] mutation causes lysosomal dysfunction, activates LRRK2, and promotes the lysosomal association of RILPL1 and TMEM55B through phosphorylation of Rab proteins.

GlypNirO: An automated workflow for quantitative N- and O-linked glycoproteomic data analysis

GlypNirO automates quantitative glycoproteomic analysis by integrating Byonic and Proteome Discoverer outputs, identifying glycosylation changes in hepatocellular carcinoma as potential biomarkers.

DIALib: an automated ion library generator for data independent acquisition mass spectrometry analysis of peptides and glycopeptides

DIALib automates the creation of DIA ion libraries for peptides and glycopeptides, enabling unbiased analysis of glycoproteomes without prior glycan knowledge.