Author

Ying Sun

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-2979-4735Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ying Sun9 papers · Capital Medical University

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Abhrarup RoyiD· 1 shared Ahmet KaynakiD· 1 shared Allison Deogaygay· 1 shared Benjamin LiouiD· 1 shared Cheng ZhangiD· 1 shared Christopher N. MayhewiD· 1 shared Chun ZengiD· 1 shared Daniel H. Paushter· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBioinformatics

Abhrarup RoyORCID

Author profile →

4 papers

Recent·Most cited

Patient-Specific Midbrain Organoids with CRISPR Correction Recapitulate Neuronopathic Gaucher Disease Phenotypes and Enable Evaluation of Novel Therapies

Yi Lin, Benjamin Liou, Venette Fannin, Stuart Adler, Christopher N. Mayhew, Jason E. Hammonds, Yueh‐Chiang Hu, Jason H. Tchieu, Wujuan Zhang, Xueheng Zhao, Rebecca L. Beres, Kenneth D.R. Setchell, Ahmet Kaynak, Xiaoyang Qi, Ricardo A. Feldman, Ying Sun

This paper develops patient-specific midbrain organoids with CRISPR correction to model neuronopathic Gaucher disease and test therapies.

bioRxiv · Nov 6, 2025Neuroscience

Single cell chromatin accessibility reveals pancreatic islet cell type- and state-specific regulatory programs of diabetes risk

Joshua Chiou, Chun Zeng, Cheng Zhang, Jee Yun Han, Michael Schlichting, Michael Miller, Robert Mendez, Serina Huang, Jinzhao Wang, Yinghui Sui, Allison Deogaygay, Mei-Lin Okino, Yunjiang Qiu, Ying Sun, Parul Kudtarkar, , Kyle J. Gaulton

The paper uses single-cell chromatin accessibility to identify cell type- and state-specific regulatory programs associated with type 2 diabetes risk.

Nature Genetics · Apr 1, 2021Peer-reviewedGenomics

SeqEnhDL: sequence-based classification of cell type-specific enhancers using deep learning models

Yupeng Wang, Rosario B. Jaime-Lara, Abhrarup Roy, Ying Sun, Xinyue Liu, Paule V. Joseph

SeqEnhDL classifies cell type-specific enhancers using deep learning, outperforming existing methods and directly distinguishing enhancers from different cell types.

BMC Research Notes · Mar 19, 2021Peer-reviewedBioinformatics

Progranulin deficiency leads to reduced glucocerebrosidase activity

Xiaolai Zhou, Daniel H. Paushter, Mitchell D. Pagan, Dong-Sung Kim, Mariela Nunez Santos, Raquel L. Lieberman, Herman S. Overkleeft, Ying Sun, Marcus Bustamante Smolka, Fenghua Hu

This study shows that progranulin deficiency reduces glucocerebrosidase activity, linking it to lysosomal dysfunction in neurodegenerative diseases.

PLoS ONE · Jul 10, 2019Peer-reviewedNeuroscience