Author

Sabine Lagger

University of Veterinary Medicine ViennaORCID 0000-0002-3032-9910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian Peter BirdiD· 1 shared Bernard H. Ramsahoye· 1 shared Boris TichýiD· 1 shared Christian SeiseriD· 1 shared Christina SternbergiD· 1 shared Chuan HeiD· 1 shared Daniela ZwolanekiD· 1 shared Desiree Lindner· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Adrian Peter BirdORCID

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2 papers

Recent·Most cited

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

Christina Sternberg, Martin Raigel, Tanja Limberger, Karolína Trachtová, Michaela Schlederer, Desiree Lindner, Petra Kodajova, Jiaye Yang, Roman Ziegler, Jessica Kalla, Stefan Stoiber, Saptaswa Dey, Daniela Zwolanek, Heidi Anne Neubauer, Monika Oberhuber, , Lukas Kenner

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

Molecular Cancer · Oct 31, 2024Peer-reviewedCancer Biology

Domains of methylated CAC and CG target MeCP2 to tune transcription in the brain

Sabine Lagger, John C. Connelly, Gabriele Schweikert, Shaun Webb, Jim Selfridge, Bernard H. Ramsahoye, Miao Yu, Dina DeSousa, Christian Seiser, Chuan He, Guido Sanguinetti, Lawrence C. Sowers, Malcolm D. Walkinshaw, Adrian Peter Bird

The paper shows MeCP2 binds to mCG and mCAC sequences in mouse brain, with binding density correlating with transcriptional regulation of neuronal genes.

PLoS Genetics · May 12, 2017Peer-reviewedMolecular Biology