Scott W. Woods

Personalized disordered circuit modeling reveals diverse neurobiological routes to transdiagnostic symptoms

The paper develops a data-driven method to identify individualized disordered connectivity patterns from fMRI data, revealing diverse neurobiological mechanisms underlying transdiagnostic psychiatric symptoms.

Testing the Tests: Using Connectome-Based Predictive Models to Reveal the Systems Standardized Tests and Clinical Symptoms Are Reflecting

This paper introduces a feedback approach to connectome-based predictive modeling to identify which brain systems standardized tests and clinical symptoms reflect, enabling better-targeted test development.

Flexible brain state engagement predicts cognitive control transdiagnostically

This study shows that flexible brain state engagement predicts cognitive control across multiple psychiatric disorders using machine learning and three transdiagnostic datasets.

Transdiagnostic connectome-based predictive modeling reveals where circuits related to self-reported clinical symptoms impinge upon brain networks supporting cognition

The paper uses connectome-based predictive modeling to show that circuits related to clinical symptoms and cognitive deficits are localized in specific brain networks.

Unique functional neuroimaging signatures of genetic versus clinical high risk for psychosis

The paper compares functional brain measures between 22qDel and CHR cohorts, finding distinct patterns of connectivity and variability disruptions.

Linking Choroid Plexus Enlargement with Plasma Analyte and Structural Phenotypes in Clinical High Risk for Psychosis: A Multisite Neuroimaging Study

This study finds that individuals at clinical high risk for psychosis have larger choroid plexus volumes, associated with neuroanatomical changes and plasma analyte markers.

Genetic and clinical analyses of psychosis spectrum symptoms in a large multi-ethnic youth cohort reveal significant link with ADHD.

The paper investigates genetic risk for psychosis spectrum symptoms in youth, finding a significant link with ADHD polygenic scores and age-specific effects.

Reliability of Mismatch Negativity Event-Related Potentials in a Multisite, Traveling Subjects Study

The paper evaluates MMN reliability across multiple EEG sites using different preprocessing methods, finding that mastoid referencing improves reliability.

Progressive reconfiguration of resting-state brain networks as psychosis develops: Preliminary results from the North American Prodrome Longitudinal Study (NAPLS) consortium

The paper examines longitudinal changes in resting-state brain networks in individuals at clinical high risk for psychosis and finds reduced network efficiency and increased diversity in those who later develop psychosis.

Toward leveraging big data in human functional connectomics: Generalization of brain graphs across scanners, sessions, and paradigms

The paper assesses the reliability of functional connectomic measures across different scanners, sessions, and paradigms, finding fair to excellent reliability and demonstrating achievable statistical power in multisite studies.