Elaine F. Walker

Synaptic microRNA dysregulation orchestrates aberrant glutamatergic transmission in a human neuronal model of 22q11.2 deletion syndrome

This study identifies dysregulated synaptic microRNAs in 22q11DS neurons that drive aberrant glutamatergic transmission and synaptic plasticity, linking genetic deletion to psychosis risk.

Unique functional neuroimaging signatures of genetic versus clinical high risk for psychosis

The paper compares functional brain measures between 22qDel and CHR cohorts, finding distinct patterns of connectivity and variability disruptions.

Visual-motor integration deficits in 3q29 deletion syndrome

This study examines visual-motor integration deficits in 3q29 deletion syndrome, finding significant gender differences and associations with ADHD and cognitive ability.

The clinical phenotype of autism spectrum disorder in individuals with 3q29 deletion syndrome

This study evaluates clinical features of autism spectrum disorder in individuals with 3q29 deletion syndrome using standardized assessments, finding increased social disability in those without ASD and preserved social communication in those with ASD.

Linking Choroid Plexus Enlargement with Plasma Analyte and Structural Phenotypes in Clinical High Risk for Psychosis: A Multisite Neuroimaging Study

This study finds that individuals at clinical high risk for psychosis have larger choroid plexus volumes, associated with neuroanatomical changes and plasma analyte markers.

A distinct cognitive profile in individuals with 3q29 deletion syndrome

This study evaluates cognitive profiles in individuals with 3q29 deletion syndrome, finding verbal ability strengths and associations with intellectual disability and adaptive behavior.

Convergent and distributed effects of the schizophrenia-associated 3q29 deletion on the human neural transcriptome

This study investigates the molecular effects of the 3q29 deletion on the human neural transcriptome, identifying convergent and distributed impacts across gene clusters and pathways related to psychiatric disorders.

Comprehensive phenotyping of 3q29 deletion syndrome: recommendations for clinical care

This study evaluates 32 individuals with 3q29 deletion syndrome to identify common medical and neurodevelopmental features and provides clinical care recommendations.

Genetic and clinical analyses of psychosis spectrum symptoms in a large multi-ethnic youth cohort reveal significant link with ADHD.

The paper investigates genetic risk for psychosis spectrum symptoms in youth, finding a significant link with ADHD polygenic scores and age-specific effects.

Reliability of Mismatch Negativity Event-Related Potentials in a Multisite, Traveling Subjects Study

The paper evaluates MMN reliability across multiple EEG sites using different preprocessing methods, finding that mastoid referencing improves reliability.

Progressive reconfiguration of resting-state brain networks as psychosis develops: Preliminary results from the North American Prodrome Longitudinal Study (NAPLS) consortium

The paper examines longitudinal changes in resting-state brain networks in individuals at clinical high risk for psychosis and finds reduced network efficiency and increased diversity in those who later develop psychosis.

Toward leveraging big data in human functional connectomics: Generalization of brain graphs across scanners, sessions, and paradigms

The paper assesses the reliability of functional connectomic measures across different scanners, sessions, and paradigms, finding fair to excellent reliability and demonstrating achievable statistical power in multisite studies.