Author

Ayako Fukunaka

Gunma UniversityORCID 0000-0002-3134-6915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Gen TanakaiD· 2 shared Izuho HatadaiD· 2 shared Takashi SatoiD· 2 shared Takuro HoriiiD· 2 shared Toshiyuki FukadaiD· 2 shared Yoshio FujitaniiD· 2 shared Atsushi HijikataiD· 1 shared Ayaka Noguchi· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Gen TanakaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of a Selective Inhibitor of ZIP14 with Therapeutic Potential for Cancer-associated Cachexia

Takafumi Hara, Gen Tanaka, Tomonori Tamura, Masaomi Terajima, Kengo Hamamura, Yuya Yoshida, Tohru Kimura, Yusuke Kasai, Yuta Nakayama, Takumi Umeyama, Kohei Hosoi, Ayaka Noguchi, Yasuno Nakai, Atsushi Hijikata, Koji Matsukawa, , Toshiyuki Fukada

This paper identifies PPTD, the first selective ZIP14 inhibitor, showing it reverses ZIP14-driven cytotoxicity and ameliorates cancer cachexia in mice.

bioRxiv · Oct 23, 2025 · PreprintBiochemistry

Glucagon dysfunction in the liver induces hyperplasia of PP cells and the production of glucagon and pancreatic polypeptide double-positive cells

Yuko Nakagawa, Takuro Horii, Ayako Fukunaka, Takashi Sato, Masaki Kobayashi, Tadahiro Kitamura, Yoshitaka Hayashi, Takashi Nishimura, Izuho Hatada, Yoshio Fujitani

The paper shows that glucagon dysfunction in the liver leads to PP cell hyperplasia and the emergence of GCG+ PP+ double-positive cells through hyperaminoacidemia and mTOR signaling.

bioRxiv · Feb 27, 2025 · PreprintCell Biology

ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance

Ayako Fukunaka, Gen Tanaka, Tōru Kimura, Kowit Hengphasatporn, Daisuke Saito, Mayo Shigeta, Hiroshi Shibata, Takayuki Ichinose, Ichitaro Abe, Mari Shimura, Takashi Sato, Yuko S. Nakagawa, Takuro Horii, Izuho Hatada, Shingo Kajimura, , Yoshio Fujitani

This study shows ZIP13 regulates lipid metabolism by modulating intracellular iron and zinc balance in adipocytes.

bioRxiv · Jul 3, 2024 · PreprintCell Biology