Author

Si-Nan Zhai

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Aayushi P. Shah· 1 shared Bang-Qi Zhu· 1 shared Bowen JiangiD· 1 shared Christopher J. FieldsiD· 1 shared Chu‐Xiao LiuiD· 1 shared Deirdre C. Tatomer· 1 shared Dongming LiangiD· 1 shared Hao WuiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Aayushi P. Shah

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2 papers

Recent·Most cited

Circular RNA aptamers ameliorate AD-relevant phenotypes by targeting PKR

Xin Feng, Bowen Jiang, Si-Nan Zhai, Chu‐Xiao Liu, Hao Wu, Bang-Qi Zhu, Meng-Yuan Wei, Jia Wei, Li Chun Yang, Ling‐Ling Chen

The paper shows that circular RNAs targeting PKR reduce neuroinflammation and amyloid-beta plaques in AD mouse models.

bioRxiv · Mar 27, 2024 · PreprintMolecular Biology

IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events

Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Aayushi P. Shah, Matthew P. Tracey, Xu-Kai Ma, Christopher J. Fields, Maria Saraí Mendoza-Figueroa, Michele C. Meline, Deirdre C. Tatomer, Li Yang, Jeremy E. Wilusz

The paper shows that IntS6 recruits PP2A to regulate transcription termination efficiency at specific genes, highlighting the phosphatase module's selective role in Integrator complex function.

Molecular Cell · Nov 22, 2023Peer-reviewedMolecular Biology