Author

Yoichi Mizukami

Yamaguchi UniversityORCID 0000-0002-3290-0754Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Jun MutoiD· 2 shared Keishiro IsayamaiD· 2 shared Ken ShiraishiiD· 2 shared Teruko Tsuda· 2 shared Yasuhiro FujisawaiD· 2 shared Ayami Fukuyama· 1 shared Choyo Ogasawara· 1 shared Daisuke ShiokawaiD· 1 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Jun MutoORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dietary lipid stress aggravates obstructive lung injury involving epithelial IGF-1-Akt dysfunction and epithelial-endothelial crosstalk

Choyo Ogasawara, Hirofumi Nohara, Tomoki Kishimoto, Keisuke Kawano, Kenji Watanabe, Kentaro Oniki, Yukio Fujiwara, Ryunosuke Nakashima, Shunsuke Kamei, Noriki TAKAHASHI, Megumi Hayashi, Ayami Fukuyama, Mai Uemura, Keiko Ueno-Shuto, Junji Saruwatari, , Tsuyoshi Shuto

This study shows that high-fat diet worsens obstructive lung injury by impairing epithelial IGF-1-Akt signaling and promoting epithelial-endothelial interactions.

bioRxiv · Sep 3, 2026 · PreprintMolecular Biology

High-resolution spatial profiling identifies disease-specific molecular architecture in palmoplantar pustulosis

Kazuki Yatsuzuka, Jun Muto, Yoichi Mizukami, Keishiro Isayama, Daisuke Shiokawa, Mei Miyazaki, Teruko Tsuda, Ken Shiraishi, Yasuhiro Fujisawa, Masamoto Murakami

This study uses spatial transcriptomics to identify distinct molecular patterns in PPP and DE, revealing differences in AQP3 expression and STAT3 activation.

bioRxiv · May 12, 2026 · PreprintMolecular Biology

Aberrant laminin signaling drives melanocyte dedifferentiation and unveils a tractable therapeutic target in vitiligo

Fei Yang, Lingli Yang, Sylvia Lai, Masafumi Yokota, Yasutaka Kuroda, Takuo Yuki, Yoshito Takahashi, Tetsuya Sayo, Takeshi Namiki, Hiroyuki Goto, Sho Hiroyasu, Shigetoshi Sano, SHINTARO INOUE, Yoichi Mizukami, Daisuke Tsuruta, Ichiro Katayama

This study identifies melanocyte dedifferentiation as a reversible mechanism in vitiligo and shows that targeting specific pathways can restore pigmentation.

Nature Communications · Apr 17, 2026Peer-reviewedCell Biology

Trehalose promotes wound healing in vitro by enhancing the migration of human keratinocytes via the VEGF/JNK/PI3K pathway

Keigo Taneda, Xiuju Dai, Kenji Watanabe, Teruko Tsuda, Hideki Mori, Ken Shiraishi, Yoichi Mizukami, Yasuhiro Fujisawa, Jun Muto

This study shows trehalose enhances keratinocyte migration and wound closure via the VEGF/JNK/PI3K pathway in vitro.

bioRxiv · Aug 25, 2025 · PreprintCell Biology

Akr1b7 functions as a master regulator in ovarian aging

Keishiro Isayama, Kenji Watanabe, Masato Ohtsuka, Seisuke Kimura, Tomoaki Murata, Takeshi Honda, Masataka Asagiri, Shun Sato, Hiroshi Tamura, Norihiro Sugino, Yoichi Mizukami

This study identifies Akr1b7 as a key regulator in ovarian aging, showing its role in oocyte maturation and estrous cycle regulation in mice.

bioRxiv · Aug 9, 2023 · PreprintMolecular Biology