Salvatore Oliviero

Post-Weaning Gut Microbiota Colonization Reveals Divergent Recovery of Skeletal Muscle and Peripheral Nerves

This study shows that post-weaning gut microbiota colonization partially restores skeletal muscle but not peripheral nerve abnormalities in germ-free mice.

Brain injury reactivates a developmental program driving genesis and integration of transient LGE-class interneurons

The paper shows that brain injury reactivates a developmental program in astrocytes to generate transient LGE-class interneurons that integrate into neural circuits.

Bedaquiline Amplifies Proteasome Inhibitor Efficacy and Overcomes Resistance in Multiple Myeloma

This paper identifies bedaquiline as a synergistic agent that enhances proteasome inhibitor efficacy and overcomes resistance in multiple myeloma and related B-cell malignancies.

TGF-beta dynamically controls epithelial identity in a 3D model of human epiblast

This study develops a 3D model of human pluripotent epiblast formation and shows that TGF-beta dynamically maintains epithelial identity, independent of canonical pluripotency markers.

FVIII interacts with cell surface to regulate endothelial cell functionality

This study shows FVIII regulates endothelial cell functionality and vessel stability, with therapeutic potential in haemophilia A.

Nr2f1 controls mitochondrial dynamics in mouse adult-born hippocampal neurons

This study shows Nr2f1 regulates mitochondrial dynamics in adult-born hippocampal neurons, linking it to BBSOAS pathogenesis.

RNABSdb and 3plex enable deep computational investigation of triplex forming lncRNAs

The paper curates a database of RNA-DNA binding sites and introduces a tool to predict RNA:DNA:DNA triple helices, showing most lncRNAs can bind the genome via this mechanism.

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain prostate cancer cell fitness

This study identifies HNRNPM as a splicing factor critical for prostate cancer cell growth by regulating splicing fidelity and circRNA biogenesis, suggesting it as a therapeutic target.