Augusto Schneider

EXOSOMES FROM CYCLIC MICE MODULATE LIVER TRANSCRIPTOME IN ESTROUPAUSE MICE INDEPENDENT OF AGE

This study shows that exosomes from cyclic mice can reverse liver transcriptome changes in estropausal mice, independent of age, by modulating miRNA content.

Effect of senolytic drugs in young female mice chemically induced to estropause

This study examines metabolic changes and senescent cell burden in young female mice with induced estropause, finding minor metabolic effects and no protective effect of senolytic drugs.

The function and decline of the female reproductive tract at single-cell resolution

This study maps the single-cell transcriptional and morphological changes in the mouse female reproductive tract across the estrus cycle, decidualization, and aging, revealing age-related fibrosis and inflammation.

Growth hormone receptor (GHR) in AgRP neurons regulatesthermogenesis in aged mice in a sex-specific manner

This study shows that GHR in AgRP neurons affects thermogenesis in aged mice, with sex-specific differences in body temperature and BAT gene expression.

Dasatinib Plus Quercetin on Uterine Age-Related Dysfunction and Fibrosis in Mice

This study investigates the effects of dasatinib plus quercetin on uterine fibrosis in aged mice, showing increased p53 expression and reduced miR34a levels.