Author

Isabelle Méan

University of GenevaORCID 0000-0002-3453-0507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Olivier MerceyiD· 3 shared Paul GuichardiD· 3 shared Virginie HameliD· 3 shared Florent LemaîtreiD· 2 shared Adrian Müller· 1 shared Benita WolfiD· 1 shared Benjamin D. EngeliD· 1 shared Caitlyn L McCaffertyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Olivier MerceyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HAK-actin, U-ExM-compatible probe to image the actin cytoskeleton

Olivier Mercey, Luc Reymond, Florent Lemaître, Isabelle Méan, Marine Hélène Laporte, Marine Olivetta, Karin Sadoul, Omaya Dudin, Virginie Hamel, Paul Guichard

The paper introduces HAK-actin, a probe for imaging actin cytoskeleton compatible with U-ExM, showing robust staining across human cells, microbial eukaryotes, and mouse retinal tissue.

Cell Reports Methods · Apr 16, 2026Peer-reviewedCell Biology

Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy

Florent Lemaître, Olivier Mercey, Isabelle Méan, Elise Paulin, Valérie Dutoit, Jan A. Rath, Christine Von Gunten, Denis Migliorini, Caroline Arber, Paul Guichard, Virginie Hamel, Benita Wolf

This study uses cryo-expansion microscopy to visualize the nanoscale architecture of immune synapses in T cells and their interactions with tumor cells, revealing structural details of signaling molecules and lytic granules.

Cell Reports · Apr 1, 2026Peer-reviewedImmunology

The Luminal Ring Protein C2CD3 Acts as a Radial In-to-Out Organizer of the Distal Centriole and Appendages

Eloïse Bertiaux, Vincent Louvel, Caitlyn L McCafferty, Hugo van den Hoek, Umut Batman, Souradip Mukherjee, Lorène Bournonville, Olivier Mercey, Isabelle Méan, Ricardo Diogo Righetto, Adrian Müller, Philippe Van der Stappen, Garrison Buss, Jean Daraspe, Christel Genoud, , Paul Guichard

This study identifies C2CD3 as a radial organizer of the distal centriole and appendages, revealing its role in structuring the luminal ring and interacting with the DISCO complex.

PLoS Biology · Dec 9, 2025Peer-reviewedCell Biology