Author

Benita Wolf

University of GenevaORCID 0000-0001-5673-4239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Florent LemaîtreiD· 2 shared Virginie HameliD· 2 shared Alexandre DumeziD· 1 shared Anthony CornuiD· 1 shared Anthony MarchandiD· 1 shared Bruno E. CorreiaiD· 1 shared Camilla JandusiD· 1 shared Caroline ArberiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Florent LemaîtreORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

KLRG1 identifies circulating cytotoxic CD4 T cells with selective anti-tumor function in human cancer

Mara Cenerenti, Josep Garnica, Margaux Saillard, Paul Gueguen, Benita Wolf, Florent Lemaître, Romina Marone, Yen‐Cheng Liu, Anthony Cornu, Alexandre Dumez, Maria Giulia Sardiello, Robert Pick, Stéphane Jemelin, Laurence de Leval, Sabina Müller, , Camilla Jandus

This study identifies KLRG1 as a marker for cytotoxic CD4 T cells in cancer patients and shows their anti-tumor function and regulation by IL-6.

bioRxiv · Apr 14, 2026 · PreprintImmunology

Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy

Florent Lemaître, Olivier Mercey, Isabelle Méan, Elise Paulin, Valérie Dutoit, Jan A. Rath, Christine Von Gunten, Denis Migliorini, Caroline Arber, Paul Guichard, Virginie Hamel, Benita Wolf

This study uses cryo-expansion microscopy to visualize the nanoscale architecture of immune synapses in T cells and their interactions with tumor cells, revealing structural details of signaling molecules and lytic granules.

Cell Reports · Apr 1, 2026Peer-reviewedImmunology

Drug-controlled CAR-T cells through the regulation of cell-cell interactions

Leo Scheller, Greta Maria Paola Giordano Attianese, Rocío Castellanos-Rueda, Raphaël B. Di Roberto, Markus Barden, Melanie M. Triboulet, Morteza Hafezi, Sarah Ash, Sailan Shui, Elisabetta Cribioli, Patrick Reichenbach, Jimmy Maillard, Anthony Marchand, Sandrine Georgeon, Benita Wolf, , Melita B. Irving

This paper develops DROP-CARs, drug-regulated CAR-T cells that control cell-cell interactions using small-molecule switches, showing in vitro and in vivo functionality.

Nature Chemical Biology · Feb 19, 2026Peer-reviewedSynthetic Biology