Author

Elise Paulin

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Adeline CozzaniiD· 1 shared Angélina Kasprowicz· 1 shared Benita WolfiD· 1 shared Benjamin SegainiD· 1 shared Bruno QuesneliD· 1 shared Caroline ArberiD· 1 shared Christina M. RollingsiD· 1 shared Christine Von Gunten· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Adeline CozzaniORCID

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2 papers

Recent·Most cited

Lysosomal adaptation to extracellular acidity compromises CD8+ T cell cytotoxicity

Benjamin Segain, Ryan Conesa, Christina M. Rollings, Sofia Titah, Elise Paulin, Adeline Cozzani, Angélina Kasprowicz, Leila Mohammadnizad, Silvia Gaggero, Yasmine S. Touil, Ignacio Moraga, Bruno Quesnel, Rahul Roychoudhuri, Robert Eil, Linda V. Sinclair, , Suman Mitra

This study shows that chronic extracellular acidosis remodels lysosomes in CD8+ T cells, impairing their cytotoxicity by depleting granzyme B through vesicle release.

bioRxiv · Oct 27, 2026 · PreprintImmunology

Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy

Florent Lemaître, Olivier Mercey, Isabelle Méan, Elise Paulin, Valérie Dutoit, Jan A. Rath, Christine Von Gunten, Denis Migliorini, Caroline Arber, Paul Guichard, Virginie Hamel, Benita Wolf

This study uses cryo-expansion microscopy to visualize the nanoscale architecture of immune synapses in T cells and their interactions with tumor cells, revealing structural details of signaling molecules and lytic granules.

Cell Reports · Apr 1, 2026Peer-reviewedImmunology