Robert Andrews

The paper identifies GATA6's role in regulating sphingolipid and CysLT metabolism in peritoneal macrophages, leading to eosinophil survival via CysLT signaling.

This paper uses intradermal GAD-Alum challenge and scRNA-seq to identify and profile GAD-reactive T cells in type 1 diabetes.

The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.

Alox15-deficient mice heal skin punch wounds with excess collagen, low matrix metalloproteinase activity and unresolved inflammatory gene expression; topical physiological 12/15-lipoxygenase oxylipin mixtures reduced collagen and raised collagenase activity.

The paper identifies CRTAM-expressing CD4+ T-cells in lymphoid-driven synovitis and shows that IL-6 and IL-27 inhibit their activation through STAT3 and ZEB1.

This study shows that altering Spi1 levels in mouse microglia affects transcriptomic pathways, suggesting a link between Spi1 and AD-related immune responses.