Xinya Huang

This study identifies SET-19 as a somatic H3K23 methyltransferase in C. elegans and shows its role in gene repression through chromatin modifications.

This study investigates the role of GTBP-1 in heat stress response in C. elegans germline, showing its involvement in stress granule formation and reproductive homeostasis.

The paper identifies two novel proteins, EGC-2 and EGC-3, that are essential for E granule assembly and small RNA homeostasis in C. elegans using TurboID-based proximity labeling and RNAi screening.

This study shows that rRNA intermediates influence nucleolar structure in C. elegans by altering protein distribution and causing architectural changes.

The paper shows that spatial clustering of piRNA genes in nematodes enhances transcription through phase separation involving UAD-2 and the SUMO regulatory factors GEI-17 and TOFU-3.

The paper shows that TAF-12 is required for piRNA transcription in C. elegans by recruiting transcription factors and machinery to H3K27me3-enriched regions.

The paper identifies a new subnuclear organelle called the nucleolar stress body (NoSB) in C. elegans, formed through the NOSR-1/NUMR-1 axis in response to nucleolar stress.

The paper identifies peri-centrosomal localization of siRNAs in C. elegans using NRDE-3 as a reporter, showing dependence on 22G siRNAs and centrosomal components.

The paper identifies a new subcompartment in C. elegans germ granules that facilitates specialized small RNA production, essential for fertility and RNAi response.

The paper identifies a nematode gene acquired via horizontal gene transfer from bacteria that enhances stress resilience by enabling L-rhamnose biosynthesis for cuticle integrity.

The paper identifies CDE-1 as a factor that suppresses risiRNA production by polyuridylating and degrading 26S rRNA in C. elegans.