Author

Shogo Takahashi

National Institutes of HealthORCID 0000-0002-3831-5353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Frank J. GonzaleziD· 2 shared Amanda Huber· 1 shared Andrew D. PattersoniD· 1 shared Anitha Vijay Mallappa· 1 shared Carlos Ichiro Kasano-CamonesiD· 1 shared Carole A. ParentiD· 1 shared Chad N. BrockeriD· 1 shared Costas Andreas LyssiotisiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Frank J. GonzalezORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 6, 2026

Fatty acids in the tumor microenvironment reprogram neutrophils to induce immunosuppression via adenosine

Rashi Singhal, Nina W. Zhang, Zheng Hong Lee…·Yatrik Madhukar Shah

This study identifies a fatty acid-driven neutrophil-adenosine axis that promotes immunosuppression in colorectal cancer and shows that targeting adenosine receptors can enhance immunotherapy responses.

DOI 10.64898/2026.04.02.716169

mousebulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedNov 17, 2020

Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to metabolic stress

Chad N. Brocker, Donghwan Kim, Tisha Melia…·Frank J. Gonzalez

The paper shows that PPARA upregulates Gm15441, which suppresses TXNIP and reduces NLRP3 inflammasome activation during metabolic stress.

90 citationstop 3%

mouseexperimental assay

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