Author

Kevin Chiem

Texas Biomedical Research InstituteORCID 0000-0002-3892-5944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Adolfo García‐SastreiD· 2 shared Anastasija ČupićiD· 2 shared Luis Martínez‐SobridoiD· 2 shared Ahmed MostafaiD· 1 shared Aitor NogalesiD· 1 shared Alexander A. BukreyeviD· 1 shared Beatriz M. A. FontouraiD· 1 shared Chengjin YeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Adolfo García‐SastreORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Mutations in SARS-CoV-2 Nsp1 are critical determinants of viral pathogenicity in mice

Nathaniel D. Jackson, Fuchun Zhou, Anastasija Čupić, Tolga Çağatay, Haiping Hao, Vinay Shivanna, Ruby A. Escobedo, Kevin Chiem, Chengjin Ye, Lisa Miorin, Beatriz M. A. Fontoura, Adolfo García‐Sastre, Alexander A. Bukreyev, Luis Martínez‐Sobrido

This study identifies critical residues in SARS-CoV-2 Nsp1 that determine viral pathogenicity in mice by reducing replication and immune response severity.

bioRxiv · Aug 19, 2026 · PreprintMicrobiology

Bioluminescent reporter influenza A viruses to track viral infections

Ramya S. Barre, Ahmed Mostafa, Kevin Chiem, Rebecca L. Pearl, Roy N. Platt, Anastasija Čupić, Timothy J. C. Anderson, Ulla G. Knaus, Randy A. Albrecht, Adolfo García‐Sastre, James J. Kobie, Aitor Nogales, Luis Martínez‐Sobrido

This paper develops recombinant influenza A viruses expressing nanoluciferase for in vitro and in vivo tracking of viral infections, showing they replicate efficiently and can be imaged using IVIS.

Microbiology Spectrum · Oct 8, 2025Peer-reviewedMicrobiology