Lisa Miorin

This study identifies USP7 as a gene that restricts neurotropic orthoflavivirus entry by controlling endosomal dynamics, with mutations in USP7 increasing susceptibility to ZIKV infection.

This study identifies critical residues in SARS-CoV-2 Nsp1 that determine viral pathogenicity in mice by reducing replication and immune response severity.

This study investigates BANAL-236, a SARS-CoV-2-related bat virus, showing it can use human entry factors and evade human innate immunity, suggesting potential for zoonotic spillover.

This study shows that a deletion in the NSP1 protein of SARS-CoV-2 variants reduces virulence by impairing host translation shutoff, suggesting NSP1 as a target for antiviral strategies.

The paper systematically analyzes proteomic and genomic data of SARS-CoV-2 variants to identify how mutations affect viral gene expression, host interactions, and immune evasion.

Affinity-purification mass spectrometry of 26 SARS-CoV-2 proteins in HEK293T cells yields 332 high-confidence host interactions and 67 druggable human proteins with known compounds.