Author
The University of Texas Southwestern Medical CenterORCID 0000-0003-0256-7636Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nathaniel D. Jackson, Fuchun Zhou, Anastasija Čupić…·Luis Martínez‐Sobrido
This study identifies critical residues in SARS-CoV-2 Nsp1 that determine viral pathogenicity in mice by reducing replication and immune response severity.
Casey E. Wing, Ho Yee Joyce Fung, Bert Kwanten…·Yuh Min Chook
This paper reveals that SINE compounds induce XPO1 degradation via an allosteric mechanism involving ASB8, distinct from molecular glue degraders.
Chengjin Ye, Shahrzad Ezzatpour, Brian Imbiakha…·Hector C. Aguilar
This study shows that a deletion in the NSP1 protein of SARS-CoV-2 variants reduces virulence by impairing host translation shutoff, suggesting NSP1 as a target for antiviral strategies.